Journal: Sensors (Basel, Switzerland)

Article Title: Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022

doi: 10.3390/s23104831

Figure Lengend Snippet: Number of papers citing the use of a Nicoya OpenSPR by year.

Article Snippet: Qiang and coworkers directly compared the Nicoya OpenSPR (which uses localized SPR) with a Biacore SPR (using the traditional reflected angle SPR detection) to investigate the anti-inflammatory activity of the dermcidin peptide binding to the epidermal growth factor receptor (EGFR) protein and found comparable results between the two instruments [ ].

Techniques:

Journal: Sensors (Basel, Switzerland)

Article Title: Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022

doi: 10.3390/s23104831

Figure Lengend Snippet: Parameters of the Nicoya OpenSPR [ 74 ] when compared with the company’s new high-throughput SPR system Alto [ 75 , 76 ] and similar commercial instruments from Cytiva (Buckinghamshire, UK) [ 77 ] and Bruker (Billerica, MA, USA) [ 78 , 79 ]. * The baseline drift and baseline noise numbers for the OpenSPR were taken from a representative experiment carried out by our lab.

Article Snippet: Qiang and coworkers directly compared the Nicoya OpenSPR (which uses localized SPR) with a Biacore SPR (using the traditional reflected angle SPR detection) to investigate the anti-inflammatory activity of the dermcidin peptide binding to the epidermal growth factor receptor (EGFR) protein and found comparable results between the two instruments [ ].

Techniques: Injection

Journal: Sensors (Basel, Switzerland)

Article Title: Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022

doi: 10.3390/s23104831

Figure Lengend Snippet: Nicoya OpenSPR Commercial Sensor Chips Cited in Scientific Literature.

Article Snippet: Qiang and coworkers directly compared the Nicoya OpenSPR (which uses localized SPR) with a Biacore SPR (using the traditional reflected angle SPR detection) to investigate the anti-inflammatory activity of the dermcidin peptide binding to the epidermal growth factor receptor (EGFR) protein and found comparable results between the two instruments [ ].

Techniques:

Journal: Sensors (Basel, Switzerland)

Article Title: Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022

doi: 10.3390/s23104831

Figure Lengend Snippet: Applications of the OpenSPR to different kinds of molecular interactions and analytical targets. ( A ) The number of papers investigating each type of binding system, with several papers investigating more than one category. The “other interaction types” category were pairs of ligand–analyte interactions that were only cited by one paper each and includes carbohydrate–carbohydrate, polymer–small molecule, peptide–lipid, protein–virus, carbohydrate–peptide, polymer–protein, and nanofiber–protein. Papers that were characterizing nanoparticles [ , , ] or surface aggregation were omitted as they were investigating something other than a binding interaction. ( B ) The number of papers that investigated each type of target.

Article Snippet: Qiang and coworkers directly compared the Nicoya OpenSPR (which uses localized SPR) with a Biacore SPR (using the traditional reflected angle SPR detection) to investigate the anti-inflammatory activity of the dermcidin peptide binding to the epidermal growth factor receptor (EGFR) protein and found comparable results between the two instruments [ ].

Techniques: Binding Assay, Polymer, Virus